Neurotoxins

Mechanism of tetanus

The tetanus is an obligatory anaerobic bacillus produces neurotoxins that block of neurotransmitter release from spinal inhibitory interneurons, such as glycine and GABA and travel along peripheral nerves to the central nervous system.

This mechanism is very similar with other neurotoxin called botulinum, who inhibit of acetylcholine release at the neuromuscular junction, but the different the tetanus make a spastic paralysis affecting the whole body, as skeletal muscles or can cause cardiac arrhythmias and fluctuations in blood pressure.

The first bacterium infect named has no cure, but exist a vaccine can easily prevent the infection. Without this necessary prevention the person contracted the infection eventually causing death, sometimes for asphyxia, autonomic dysfunction or bronchopneumonia.

Mechanism of botulism

As you can see, this infection is one of the most dangerous in the world, because attack many organs from the brain to the muscles. For this reason, it is important for investigate and understand for eliminated or use it in other forms, which it happens with the botulinum neurotoxin that is occupied in the aesthetic companies with purpose of temporarily paralyzing smoothing of facial wrinkles call in the trade “Botox”.

Ideas how are they changing the dangerous functions of bacteria.